Charlotte Schott grew up in Neu-Isenburg. She was the daughter of the Neu-Isenburg couple Lion and Selma Schott née Cahn. The family lived in Frankfurt, Straße 32, in the parental home of Selma Schott. Lion Schott, a professional merchant, together with his father-in-law, Isaak Cahn, ran his business of "Manufactured Goods" on the ground floor of the house where the Schotts lived.

It is not known why Charlotte lived in the Home of the Jewish Women’s Association in 1938. It is likely that her stay coincided with the events of the pogrom on November 10, during which the Schott family was also attacked.

On December 12, 1938, Charlotte was moved from Neu-Isenburg to Brussels. Perhaps the parents sent their eight-year-old daughter to Belgium with one of the "children's transports" which rescued Jewish children from Germany after the Pogrom. The Schotts probably also had relatives in Brussels.

However, Charlotte returned two years later to her parents in Neu-Isenburg at the beginning of December 1940. It was no longer safe after the invasion of the German Wehrmacht in neutral Brussels in May 1940. There is some evidence that the parents brought back their daughter because the family wanted to immigrate to Lisbon together. These plans were however abandoned.

The House and land at Frankfurt Str. 32 were forcibly sold in 1938. In 1941, the Schott family together with Selma Schott’s sister Gitella and her husband Isaak Cahn lived in an apartment with three tiny rooms (a total of 22 square meters for five persons). According to an official document, because of the lack of space, the female members of the two families stayed overnight in the Jewish Women's Association home and initially in a house at Taunusstraße 9. In the spring of 1941, the two families were compulsorily admitted to “Heim Isenburg” in Taunusstraße 7.

When the Jewish Women's League home was dissolved in the spring of 1942, the Schotts apparently still stayed a few months in Neu-Isenburg. They were still reported in Frankfurt Straße 32. Lion Schott had to work forced labor as a warehouse employee at the Karl Nagel Company in Frankfurt. For this, he received permission from the mayor of Neu-Isenburg to leave the city daily and return.

At the end of September 1942, Charlotte Schott was taken to Darmstadt together with her parents. On September 30, 1942, they were deported from there to the Lublin district. On the same transport were also Charlotte's Aunt Gitella and the Neu Isenburg couple Willi and Regina Schlamm. They were probably murdered at the Treblinka extermination camp. Charlotte Schott was 12 years old at the time of her deportation.

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