Ruth Weis was the daughter of the cattle merchant Jakob Weis and his wife, Cilli née Pressburger. The family lived in Altdorf near Ettlingen in Württemberg first in Ettenheimer Straße 7 and later in a newly built house in Löwenstraße 11.

Her parents had died when Ruth was taken as a "house help" in the Neu-Isenburg Home of the Jewish Women’s Association at the age of 23. Her father is no longer listed in the Altdorfer "List of Jews" of 11 July 1938.

Ruth Weis moved from Rexingen (now the city of Horb am Neckar) to Neu-Isenburg. She lived there in the Home of the Jewish Women’s Association until the closure of the establishment. On 18 March 1942, she left for Delmensingen. Since 20 March 1942, she was registered as a ''trainee'' in the Jewish retirement home where the Jewish People are forced in. Three months later, on 10 July 1942, the 25-year-old Ruth Weis was brought away from there, on 13 July 1942, she was deported from Stuttgart via Munich to the Auschwitz concentration and extermination camp. No trace of her exists there on.

Sources: Stadtarchiv Neu-Isenburg; Memorial Book - Victims of the Persecution of Jews under the National Socialist Tyranny in Germany  1933 - 1945 (Bundesarchiv - National Archives); Die Opfer der nationalsozialistischen Judenverfolgung in Baden-Württemberg 1933 - 1945. Ein Gedenkbuch; this biography could be completed by the support of Dr. Michael Koch, Museum zur Geschichte von Christen und Juden, Laupheim